一、个人简介
职称:教授
学位:博士
导师:生物学 博士研究生导师
生物学 硕士研究生导师
籍贯:江西南昌
二、学习和工作经历
学习经历:
2001.09-2005.04 就读于江南大学发酵工程专业获博士学位
1998.09-2001.07 就读于南昌大学食品科学专业获硕士学位
1988.09-1992.07 就读于江西工业大学粮食工程专业获学士学位
工作经历:
2005.07-至今 江西师范大学
1992.10-1998.08 江西省远东节能热点开放总公司
三、研究方向
食品生物化学、微生物学及食品安全与检测
四、主持的项目
1.2020年,江西省自然科学基金重点项目,钝齿棒杆菌CobB对精氨酸生物合成影响的机制研究(20202ACBL205001)
2.2019年,国家自然科学基金:Tween40与DtsR1对钝齿棒杆菌精氨酸生物合成网络的影响机制研究(31960014)
3.2016年,主持江西省“5511”优势科技创新团队项目,高品质鱼鳞明胶制备的关键技术中试(20165BCB19004),2019年结题
4.2016年,主持国家自然科学基金:钝齿棒杆菌FarR蛋白对精氨酸生物合成网络的调控机制及其与ArgR的关系研究(31660019),2020年结题
5.2013年,主持国家自然科学基金:基于基因组测序及基因组尺度代谢网络分析的钝齿棒杆菌产精氨酸分子育种研究(31360219), 2017年结题
6.2011年,主持国家自然科学基金:建立无毒ELISA体系检测食用油中苯并芘的方法学研究(31160323),2015年结题
7.2009年,主持国家自然科学基金:钝齿棒杆菌精氨酸生物合成途径中argR基因调控机制的研究(30960012),2012年12月结题
五、论文和专利
1.论文
[1]Mingzhu Huang, Lingfeng Zhu, Lin Feng, Li Zhan, Yue Zhao, Xuelan Chen*; Reforming nitratemetabolism for enhancing L-arginine production in Corynebacterium crenatum under oxygen limitation. Frontiers in Microbiology, 2022, 13: 834311-834321
[2] Bao Gao, Tongtong Ma, Lin Feng, Xiaolin Huang, Xuelan Chen*, YonghuaXiong*. Light scattering intensity as signal transducer to enhance the performance of immunoassay for Cronobacter detection in powdered infant formula. Sensors and Actuators B: Chemical. 2021, 344:130312-130321
[3] Zhuolin Song, Lin Feng, Yuankui Leng*, Mingzhu Huang, Hao Fang, Weipeng Tong, Xuelan Chen*, Yonghua Xiong. Dramatically enhancing the sensitivity of immunoassay for ochratoxin A detection by cascade-amplifying enzyme loading. Toxins, 2021, 13: 781-791
[4] Hao Fang, Shengnan Zhan, Lin Feng, Xuelan Chen*, Qian Guoa, Yuqian Guoa, Qinghua He*, Yonghua Xiong*. Chemical modification of M13 bacteriophage as nanozyme container for dramatically enhanced sensitivity of colorimetric immunosensor. Sensors and Actuators: B. Chemical. 2021, 346:130368-130376
[5]Mingzhu Huang, Yue Zhao, Lin Feng, Lingfeng Zhu, Li Zhan, Xuelan Chen*. Role of the ClpX from Corynebacterium crenatum involved in stress responses and energy metabolism. Applied Microbiology and Biotechnology, 2020, 104 (12):5505–5517
[6]Mingzhu Huang, Yue Zhao, Lin Feng, Lingfeng Zhu, Li Zhan, Xuelan Chen*. Role of ClpB From Corynebacterium crenatum in Thermal Stress and Arginine Fermentation. Frontiers in Microbiology, 2020, 11:1660-1671
[7] Mingzhu Huang, Yue Zhao, Rong Li, Weihua Huang, Xuelan Chen*. Improvement of L-arginine production by in silico genome-scale metabolic network model guided genetic engineering. 3 Biotech, 2020,10:126-135
[8] Yaofeng Zhou, Sicheng Xiong, KangKang Zhang, Lin Feng, Xuelan Chen*, Yuhao Wu, Xiaolin Huang, and Yonghua Xiong*. Quantum bead-based fluorescence-linked immunosorbent assay for ultrasensitive detection of aflatoxin M1 in pasteurized milk, yogurt, and milk powder. Journal of Dairy Science. 2019, 102:3985–3993
[9] Yunqing Wu, Ying Xiong, Xuelan Chen*, Dan Luo, Bao Gao, Jing Chen, Xiaolin Huang, Yuankui Leng, Yonghua Xion*.Plasmonic ELISA based on DNA-directed gold nanoparticle growth for Cronobacter detection in powdered infant formula samples. Journal of Dairy Science.2019, 102:10877–10886
[10] Minliang Chen, Xuelan Chen*, Fang Wan, Bin Zhang, Jincong Chen and Yonghua Xiong*.Effect of Tween 40 and DtsR1on l-arginine overproductionin Corynebacterium crenatum.Microbial Cell Factories, 2015, 14:119-129
2. 专利
[1] 陈雪岚,赖木兰, 李蓉. 一种合成精氨酸的方法, 2021-11-30, 中国, ZL 2018105572283.8
[2] 陈雪岚, 赖卫华,熊勇华, 魏华,李林. 检测氯胺酮和甲基苯丙胺的荧光微球免疫层析检测卡及其制备方法, 2013-04-23, 中国, ZL 200910085054.1
[3] 熊勇华, 赖卫华,魏华, 史爱武, 陈雪岚,徐波. 一种荧光微球免疫层析试纸条的制备方法及定量检测方法.2012-06-27, 中国,ZL 200910117820.8
[4]魏华,熊勇华, 赖卫华, 陈雪岚, 金晶, 李林, 陈媛. 检测残留兽药的荧光微球免疫层析试纸条及其制备方法. 2012=08-08, 中国,ZL 200710166166.0